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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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ehd123 ehd123
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10 years ago
What are genome-wide dN/dS ratios?
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B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

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#1
Staff Member
Educator
10 years ago
The dN/dS ratio is used to infer the direction and magnitude of natural selection acting on protein coding genes. A ratio greater than one implies positive or Darwinian selection; less than one implies purifying (stabilizing) selection; and a ratio of one indicates neutral (i.e. no) selection. However, a combination of positive and purifying selection at different points within the gene or at different times along its evolution may cancel each other out, giving an average value that may be lower, equal or higher than one.
Mastering in Nutritional Biology
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ehd123 Author
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#2
Valued Member
10 years ago
Thank you padre Slight Smile
One more question, what is stabilizing selection? Could you give an example?
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#3
Staff Member
Educator
10 years ago
OK sure

Stabilizing selection is the process of ongoing introduction of variation and ongoing reduction in variation. It balances out because the more introduction of variation there is, the stronger selection becomes.
Mastering in Nutritional Biology
Tralalalala Slight Smile
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