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Aripiprazole (Abilify) has been called a third-generation antipsychotic. What is a major difference ...

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Aripiprazole (Abilify) has been called a third-generation antipsychotic. What is a major difference ...

Aripiprazole (Abilify) has been called a third-generation antipsychotic. What is a major difference in its pharmacological profile from that of 1st and 2nd generation antipsychotic drugs?

a. Abilify blocks 5-HT2A receptors, whereas 1st and 2nd generation antipsychotic drugs act as agonists at 5-HT2A receptors
b. Abilify blocks dopamine D2 receptors, whereas 1st and 2nd generation antipsychotic drugs act as agonists at dopamine D2 receptors
c. Abilify is a partial agonist at dopamine D2 receptors, whereas 1st and 2nd generation antipsychotic drugs act as antagonists or inverse agonists at dopamine D2 receptors

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