Major cell cycle checkpoints

Genetic mechanisms monitor cell cycle checkpoints to ensure the cell’s readiness to progress to the next stageGenetic mechanisms monitor cell cycle checkpoints to ensure the cell’s readiness to progress to the next stage

G2 check- Metaphase checkpoint: point: Pass if Pass it all chromosomes cell size is are attached to mitotic adequate and spindle. chromosome ' *********************************************************************** replication is successfully completed. \\ \\ \\ ““053 Q 57" U C O u Q) m (/1 I (of: VNQ 3 S-phase checkpoint: G1 checkpoint: Pass if DNA replica— Pass it cell size is tion is complete and adequate, nutrient avail- has been screened to ability is sufficient, and remove base-pair growth factors (signals mismatch or error. from other cells) are present.