Acyl carrier protein

chels194

wrote...

13 years ago

In lipogenesis, acetyl and acyl molecules are activated by an acyl carrier protein (ACP).

Is this statement true? Is this the protein that activates acetyl and malonyl groups by binding to them.

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bio_man

wrote...

Educator

13 years ago

I don't think it "activates" it. Isn't that the job of fatty acyl-coa synthetase? Fatty acyl-coa synthetase is used to activate a fatty acid with acetyl-coa for transport to the plasma membrane: r-coo- + acetyl-coa => acyl-coa.

Thus, fatty acyl Coa synthetase is the commited step in fatty acid b-oxidation.

Fatty acids must also be activated in order to be converted by desaturases or elongases; in other words, they have to be activated.

ACP is just an acyl group carrier

Bio_man 8)

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chels194 Author

wrote...

13 years ago

What other is true for the following in regards of first cycle of fatty acid synthesis?

-The first cycle of lipogenesis yields CO2, 1NADP+, and an acyl group attached to ACP.

-In lipogenesis, acetyl and acyl molecules are activated by an acyl carrier protien

- Each cycle lengthens the fatty acid chain by three carbon atoms.

**in the hint that was given, it says "consider which protein activates acetyl and malonyl groups by binding to them.

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