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Softball612 Softball612
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6 years ago
In regard to killer-cell immunoglobulin-like receptors (KIRs) indicate which of the following statements is true (T) or false (F).
 
  ___ a. KIRs have a broader range of specificity for HLA class I compared with CD94:NKG2A.
  ___ b. KIRs are activating receptors of NK cells and stimulate the release of perforin and granzyme.
  ___ c. KIRs bind to monomorphic determinants on HLA-A, -B, and -C molecules.
  ___ d. All HLA-C allotypes are suitable ligands for KIRs.
  ___ e. KIRs are encoded in the leukocyte receptor complex (LRC) on chromosome 19.
  ___ f. MIC-A and MIC-B are suitable ligands for KIRs.
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6 years ago
aF; bF; cF; dT; eT; fF
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