Which of the following statements about Notch 1 is correct? (Select all that apply.)

Which of the following statements about Notch 1 is correct? (Select all that apply.)
 
  a. Notch 1 is expressed on thymic epithelial cells.
  b. In the absence of Notch 1 expression, T cells can complete their differentiation.
  c. Notch 1 is to T-cell development as Pax-5 is to B-cell development.
  d. Notch 1 contains two distinct domains, one of which is proteolytically cleaved and becomes a transcription factor in the nucleus.
  e. The extracellular domain of Notch 1 must interact with a ligand on thymic epithelium to initiate cleavage and separation of the Notch 1 extracellular and intracellular domains.