A patient has symptoms of adrenocorticoid insufficiency and is having diagnostic testing with ...

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Rationale 1: If the adrenal gland responds by secreting corticosteroids after the cosyntropin injection, the pathology lies at the level of the pituitary or hypothalamus (secondary adrenocortical insufficiency).
Rationale 2: Carpal spasms are not related to this test.
Rationale 3: The test involves plasma levels of cortisol.
Rationale 4: Flushing is not related to this test.

Global Rationale: If the adrenal gland responds by secreting corticosteroids after the cosyntropin injection, the pathology lies at the level of the pituitary or hypothalamus (secondary adrenocortical insufficiency). Carpal spasms and flushing are not related to this test. The test involves plasma levels of cortisol.

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