A client is given tamsulosin (Flomax) for benign prostatic hyperplasia (BPH). The nurse knows that ...

Correct Answer: 1
Rationale 1: Alpha1 receptors in the smooth muscle in the trigone and sphincter muscles at the base of the urinary bladder and in the prostate are blocked by this drug, causing relaxation of these muscles and an increase in the urine flow in clients who have difficulty voiding.
Rationale 2: Alpha2 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the alpha2 receptors.
Rationale 3: Beta2 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the beta2 receptors.
Rationale 4: Beta1 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the beta1 receptors.
Global Rationale: Alpha1 receptors in the smooth muscle in the trigone and sphincter muscles at the base of the urinary bladder and in the prostate are blocked by this drug, causing relaxation of these muscles and an increase in the urine flow in clients who have difficulty voiding. Alpha2 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the alpha2 receptors. Beta2 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the beta2 receptors. Beta1 receptors are not seen in the smooth muscles of the urinary bladder. Also, tamsulosin is an alpha1-blocking agent and does not affect the beta1 receptors.