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Home Q & A Board Biology-Related Homework Help Medicine Nursing and Clinical
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18ryanmandich 18ryanmandich
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6 years ago
Which statements about the differences between first- and fourth-generation cephalosporins are correct? (Select all that apply.)
 
  a. Fourth-generation agents have more activity against gram-negative organisms.
  b. First-generation agents are more active against anaerobes.
  c. First-generation agents have increased resistance to beta-lactamases.
  d. Fourth-generation agents have an increased ability to reach the cerebrospinal fluid.
  e. First-generation agents are more vulnerable to destruction by beta-lactamases.
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#1
6 years ago
ANS: A, D, E
Fourth-generation agents have more activity against gram-negative organisms and have an increased ability to reach the cerebrospinal fluid. First-generation agents are more vulnerable to destruction by beta-lactamases.
First-generation agents are not more active against anaerobes, nor do they have increased resistance to beta-lactamases.
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