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Mica121 Mica121
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6 years ago
A nurse is obtaining a drug history from a patient about to receive sulfadiazine. The nurse learns that the patient takes warfarin, glipizide, and a thiazide diuretic. Based on this assessment, the nurse will expect the provider to:
 
  a. change the antibiotic to TMP/SMZ.
  b. increase the dose of the glipizide.
  c. monitor the patient's electrolytes closely.
  d. monitor the patient's coagulation levels.
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6 years ago
D
Sulfonamides interact with several drugs and through metabolism-related interactions can inten-sify the effects of warfarin. Patients taking both should be monitored closely for bleeding ten-dencies. Changing to the combination product will not help, because sulfonamides are still present. Sulfonamides intensify glipizide levels, so this drug may actually need to be reduced. Trimethoprim, not sulfonamides, raises potassium levels.
Mica121 Author
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6 years ago
Thank you for being my superhero!
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