(Solved) In terms of energy costs to the cells in the proximal tubule, the reabsorption of salt...

HiHeyHello

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solved

14 years ago

In terms of energy costs to the cells in the proximal tubule, the reabsorption of salt...

In terms of energy costs to the cells in the proximal tubule, the reabsorption of salt (Na+ and Cl-) and water has been called a deal where we get "3 for the price of 1". Explain.

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bio_man

wrote...

Educator

14 years ago

Reabsorption in the proximal tubule is critical for the recapture of ions, water, and valuable nutrients
from the huge initial filtrate volume. NaCl (salt) in the filtrate diffuses into the cells of the transport epithelium, where Na+ is actively transported into the interstitial fluid. This transfer of positive charge out of the tubule drives the passive transport of Cl-. As salt moves from the filtrate to the interstitial fluid, water follows by osmosis. The salt and water then diffuse from the interstitial fluid into the peritubular capillaries. Glucose, amino acids, potassium ions (K+), and other essential substances are also actively or passively transported from the filtrate to the interstitial fluid and then into the peritubular capillaries.

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nite_n_day

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14 years ago

I think by drawing out the solutes from the proximal tubule, H+ ions are drawn into the priximal tubule. This makes it more acidic. To counter the acidity, urea is secreted into the nephron, which is a good thing because it is a waste product which at the same time, neutralizes the acidic concentration of filtrate. Also, the reabsorption prevents the body from losing excessive amounts of salt and water as it is reabsorbed.

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