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what is meant by synergistic action?

ehd123

wrote...

Valued Member

Posts: 778

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9 years ago

what is meant by synergistic action?

what is meant by synergistic action?

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6 Replies

B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

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Alexx

wrote...

#1

Valued Member

On Hiatus

9 years ago

I think synergic action means that, two things combined together produce an effect that is greater than the sum of the effects produced by these things idividually. See http://en.wikipedia.org/wiki/Synergy

But that is too general. You might need something more specific. Where did you found that?

Alexx

wrote...

#2

Valued Member

On Hiatus

9 years ago

For example: one person can produce 10 items per day, but if 2 people work together they can produce (together) 30 items/ day (which is more than 10+10=20)

ehd123 Author

wrote...

#3

Valued Member

9 years ago

Hi Alexx

From the article, it says "our results indicate that sox2 alone is able to induce and intermediate state and subsequent lineage specification could be accomplished upon miR-125b overexpression probably due to the synergistic action of its reported downstream targets..."

I'm assuming then it means miR-125b does its thing because it works as all the factors united? right?

B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

Alexx

wrote...

#4

Valued Member

On Hiatus

9 years ago

I think what it means is that, miR-125b overexpression activates it's targets (Lin28, p53, CDX2, STAT3, ETS1, MCL1, and IL-6), and these genes cause the lineage specification. Doesn't that make more sense?

ehd123 Author

wrote...

#5

Valued Member

9 years ago

Hmm Yup it does Flushed Face

Flushed Face

Thank you so much for the help today Alexx Slight Smile

Slight Smile

I overwhelmed you with questions Flushed Face

Flushed Face

B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

Alexx

wrote...

#6

Valued Member

On Hiatus

9 years ago

Quote

Thank you so much for the help today Alexx Smile I overwhelmed you with questions

It's ok, that's why I'm here.

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