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Sheela4875 Sheela4875
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6 years ago
Which of the following is out of order for the Merrifield solid-phase method of peptide synthesis?
  1.An amino acid is protected as a BOC-derivative.
  2.The BOC-protected amino acid is linked to the polystyrene polymer.
  3.The polymer-bound amino acid is treated with trifluoroacetic acid to remove the BOC group.
  4.A second BOC-protected amino acid is coupled to the first by reaction with DCC.
  5.All of the steps are in the correct order.
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