How is the modified amino acid selenocysteine incorporated into the enzyme formate dehydrogenase? ...

vincent_pijen

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6 years ago

How is the modified amino acid selenocysteine incorporated into the enzyme formate dehydrogenase? ...

How is the modified amino acid selenocysteine incorporated into the enzyme formate dehydrogenase?

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coupongurl69

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6 years ago

Ans: A unique Sec-tRNA recognizes a stop codon, UGA, in the mRNA by its unique secondary structure. The Sec-tRNA is generated from a Ser-tRNA by modifying serine to selenocysteine, and the SelB gene product is an elongation factor that uniquely places this modified tRNA into the A site instead of the usual EF-Tu.

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