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ronswanson11 ronswanson11
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6 years ago
Describe how the Ames test is used to determine whether a particular chemical is mutagenic.
 
  What will be an ideal response?
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6 years ago
Strains of the bacteria Salmonella typhimurium that are auxotrophic for histidine are plated on a histidine-lacking nutrient agar with rat liver cells. The unknown chemical is added to the agar plate, and the plate is observed for bacterial growth that would indicate reverse mutations caused by the chemical resulting in histidine prototrophy.
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