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jeremy.l32 jeremy.l32
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6 years ago
What was the significance of the 1978 finding by Philip Leder's research group that the 0.7 kb -globin mRNA is not colinear with the gene that encodes it, but the nuclear 1.5 kb pre-mRNA is?
 
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6 years ago
This meant that the -globin contains an intron, which is spliced out after pre-mRNA processing, and the exons are spliced together to make a mature mRNA. The significance was the realization that genes could be in pieces.
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