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mikael mikael
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12 years ago
Using the tryptophan operon as a model, explain a transcription pause site and the formation of a stem-loop.
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12 years ago
A pause in mRNA transcription occurs when tryptophan is in short supply and therefore requires the additional recruitment of a charged tryptophan tRNA for its synthesis. This lag or pause time provides the already synthesized mRNA component to bind to a different part of the transcript than would occur if there were no pause time. This different hairpin loop formed does not interact with the DNA sequence and therefore permits RNA polymerase to continue transcribing the entire mRNA, unlike what would occur if a lag time were absent.
 
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