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krazyrwe krazyrwe
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6 years ago
An area of the lung has no ventilation but is normally perfused by the pulmonary circulation. Which of the following statement(s) is/are correct?
 
  1. Blood exiting the pulmonary capillary will have a PO2 = 40 and a PCO2 = 46.
  2. The area represents an alveolar shunt.
  3. The is 0.
  a. 2 and 3 only
  b. 1 and 3 only
  c. 2 only
  d. 1, 2, and 3



Q. 2  Regarding pulmonary blood flow in the upright lung, which of the following statements is true?
 
  a. The apexes receive approximately 20 times more blood flow than the bases.
  b. The bases receive approximately 20 times more blood flow than the apexes.
  c. The greatest blood flow is found at the apexes of the lungs.
  d. The pulmonary circulation is a high-pressure system.



Q. 3  What is the normal range of PAO2  PaO2 for healthy young adults breathing room air?
 
  a. 5 to 10 mm Hg
  b. 10 to 20 mm Hg
  c. 20 to 30 mm Hg
  d. 50 to 60 mm Hg



Q. 4  In order to assess the events occurring at the tissue level, especially tissue oxygenation, what pa-rameter would you sample and measure?
 
  a. Coronary sinus blood
  b. Left-sided heart blood
  c. Systemic arterial blood
  d. Systemic mixed venous blood



Q. 5  What is the primary factor that maintains the pressure gradient that drives O2 from the capillaries into the interstitial spaces and into the cells?
 
  a. Bohr effect on the RBC
  b. Cellular consumption of O2
  c. Haldane effect on the RBC
  d. Increased carbon dioxide in blood de-creasing Hb affinity for O2
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6 years ago
(Answer to Q. 1)  ANS: D
With no ventilation to remove carbon dioxide and restore fresh O2, the makeup of gases in these areas is like that of mixed venous blood (PO2 = 40 mm Hg; PCO2 = 46 mm Hg). The / is 0. Ve-nous blood entering areas with / ratios of 0 cannot pick up O2 or unload carbon dioxide and leave the lungs unchanged. For such areas to be distinguished from true anatomical shunts, exchange units with / values of 0 are called alveolar shunts. Although small anatomical shunts are normal, alveolar shunts are not.

(Answer to Q. 2)  ANS: B
Farther down the lung, perfusion increases linearly in proportion to the hydrostatic pressure so the lung bases receive nearly 20 times as much blood flow as do the apexes.

(Answer to Q. 3)  ANS: A
Rather than equaling the alveolar PO2, the PaO2 of healthy individuals breathing air at sea level is always approximately 5 to 10 mm Hg less than the calculated PAO2.

(Answer to Q. 4)  ANS: D
To assess tissue gas exchange, the respiratory therapist must consider mixed venous blood pa-rameters. The use of mixed venous blood to assess tissue oxygenation also is discussed in Chap-ter 43.

(Answer to Q. 5)  ANS: B
As cellular metabolism depletes its O2, the intracellular PO2 drops below that of the blood enter-ing the tissue capillary. This provides the diffusion gradient by which O2 diffuses from the tissue capillary blood (PO2 = 100 mm Hg) to the cells (PO2 < 40 mm Hg).
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