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vgrdiver vgrdiver
wrote...
Posts: 527
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6 years ago
When is the rate of gaseous diffusion across a biological membrane decreased?
 
  a. The diffusion distance is small.
  b. The gas diffusion constant increases.
  c. The partial pressure gradient is low.
  d. The surface area is large.



Q. 2  What is the primary determinant of the PAO2?
 
  a. Body's CO2
  b. Metabolic rate of the body tissues
  c. PaO2
  d. PO2 in the inspired gas



Q. 3  Calculate the approximate PAO2 given the following conditions (assume R = 0.8): FiO2 = .40, PB = 770 mm Hg, PACO2 = 31 mm Hg
 
  a. 100 mm Hg
  b. 135 mm Hg
  c. 250 mm Hg
  d. 723 mm Hg



Q. 4  The PAO2 depends on which of the following factors?
 
  1. Ambient (atmospheric) pressure
  2. Fractional concentration of inspired O2
  3. Level of VA
  4. Types of fuels burned (fat, protein, and carbohydrate)
  a. 1, 2, and 3 only
  b. 1 and 2 only
  c. 3 only
  d. 1, 2, 3, and 4



Q. 5  In a person breathing room air (and with all else being normal), if the alveolar PCO2 rises from 40 to 70 mm Hg, what would you expect?
 
  a. PAO2 to fall by approximately 30 mm Hg
  b. PAO2 to fall by approximately 40 mm Hg
  c. PAO2 to rise by approximately30 mm Hg
  d. PAO2 to rise by approximately 40 mm Hg
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wrote...
6 years ago
(Answer to Q. 1)  ANS: C
Given that the area of and distance across the alveolar-capillary membrane are relatively constant in healthy people, diffusion in the normal lung mainly depends on gas pressure gradients.

(Answer to Q. 2)  ANS: D
Many factors determine the alveolar partial pressure of oxygen (PAO2). Most important is the inspired partial pressure of oxygen, or PIO2.

(Answer to Q. 3)  ANS: C
PAO2 = FiO2  (PB  47)  PACO2  0.8
where FiO2 is fraction of inspired oxygen, PB is barometric pressure, 47 is water vapor tension (in mm Hg) at 37 C, PACO2 is alveolar PCO2, and 0.8 is normal respiratory exchange ratio (R).
PAO2 = 0.4(770  47)  (31/0.8)
PAO2 = 250.45 mm Hg

(Answer to Q. 4)  ANS: D
PAO2 = FiO2  (PB  47)  PACO2  0.8
where FiO2 is fraction of inspired oxygen, PB is barometric pressure, 47 is water vapor tension (in mm Hg) at 37 C, PACO2 is alveolar PCO2, and 0.8 is normal respiratory exchange ratio (R). As the A is the primary determinant of PACO2 any changes in A will affect the PAO2. Likewise the fuel source will determine the RQ which is normally 0.8.

(Answer to Q. 5)  ANS: A
Based on the alveolar air equation, if the FiO2 remains constant, then the PAO2 must vary in-versely with the PACO2.
vgrdiver Author
wrote...
6 years ago
TY
wrote...
6 years ago
My pleasure
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