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Posts: 981
13 years ago
It was determined that something in female sex chromosomes appears to trigger a rise in blood pressure after the onset of menopause. This finding challenges the current belief that sex hormones are largely responsible for regulating blood pressure. An experiment was done with mice giving female mice the XY chromosomes and the male mice XX chromosomes. In this study, mice in which the Sry gene was deleted from the Y chromosome resulted in XY females. These mice were females because they were born with ovaries.

I think that finding what else is responsible in regulating blood pressure is a benefit for sure yet, changing the sex of mice, is something that I was ethically challenged about.

Comments? Opinions?

Article:
http://www.sciencedaily.com/releases/2010/03/100315161720.htm
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ppk
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On Hiatus
13 years ago
Good article! I found it very interesting.

Mice are used all the time for different procedures and research and this just seems to be another use for them. They are a well characterized model that is necessary to manipulate if we want to learn more about ourselves. It is sad that these experiments need to be done on mice, but personally I think it would hinder scientific progression if we did not.
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