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2 months ago
A nurse has poured a hospital patient's scheduled dose of hydrochlorothiazide (HCTZ). The nurse should know that this drug reduces preload by which of the following means?
A)Exerting a direct relaxant effect on the vascular smooth muscle
B)Increasing renal excretion of sodium and water
C)Increasing the contractility of myocardial fibers
D)Stimulating the SA node to fire more frequently
Source  Download
Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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2 months ago
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Hydrochlorothiazide inhibits the reabsorption of sodium and chloride in the distal renal tubule, increasing the excretion of sodium and water by the kidneys. Thiazide diuretics do not relax smooth muscle, increase contractility, or stimulate the SA node.

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