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2 weeks ago
A patient who is malnourished and has hypertension is being treated with losartan (Cozaar). How should the dose of the medication be adjusted in this patient?
A)The dose should be higher than normal.
B)The dose should be lower than normal.
C)The dose should remain the same as normal.
D)The medication should be combined with a diuretic.
Source  Download
Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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Both losartan and the metabolite are highly bound to plasma albumin, and losartan has a shorter duration of action. Due to malnutrition, a low dose of losartan should be prescribed. The dose should not be higher than normal due to possible toxicity. The dose should not be the same as normal due to possible toxicity. The medication will not be combined with a diuretic unless the blood pressure is not controlled.

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