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colleen colleen
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Posts: 17076
12 years ago
Compare and contrast the activities of "dicers" and "slicers."
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12 years ago
Both destroy RNA transcripts and therefore halt protein translation, but dicers and slicers target different RNA to achieve this result. Dicer is an endonuclease that cleaves dsRNA strands into small (21—23 bp) fragments called siRNA through the process of RNAi in Eukarya. The RNA-induced silencing complex (RISC) contains slicer nucleases that target ssRNA, which bind to siRNA and again are cleaved.
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