Explain why GC-rich DNA requires a higher temperature to denture or melt than AT

colleen

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12 years ago

Explain why GC-rich DNA requires a higher temperature to denture or melt than AT

Explain why GC-rich DNA requires a higher temperature to denture or melt than AT-rich DNA.

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chemb

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12 years ago

The overall increase in stability of G-C pairing should be emphasized over A-T binding. A DNA strand with high GC content (low AT) has more triple H bonds compared to an AT rich (low GC) strand of the same length contains mostly double H bonds. More energy is therefore required to break more H bonds, and thus GC rich DNA is more heat resistant to denaturation.

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