PhysioEx 8.0 Exercise 4 ACTIVITY 4 --Any help ppppplease??!!

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Activity 4: Determining the Effect of Propylthiouracil on Metabolic Rate (p. 48)

7. On the normal rat, the metabolic rate after propylthiouracil injection is slower than the
baseline metabolic rate.
Propylthiouracil is antagonistic to thyroxine and will tend to decrease the effects of
thyroxine.
On the thyroidectomized rat, the metabolic rate after propylthiouracil injection is the
same as the baseline metabolic rate.
Since the thyroidectomized rat cannot make any thyroxine, the propylthiouracil has
nothing to be antagonistic to and therefore has no effect.
On the hypophysectomized rat, the metabolic rate after propylthiouracil injection is the
same as the baseline metabolic rate.
Since the hypophysectomized rat does not have a functional thyroid gland, no thyroxine
is being made and there is nothing for the propylthiouracil to be antagonistic to.

You are a GOD-send, thank you so much!!!

Out of this entire lab book, this chapter/exercise is the only one that left me scratching my head and lost as could be! lol

Thank you so much for your help!!!! You are awesome!!!!   

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