Top Posters
Since Sunday
5
a
5
k
5
c
5
B
5
l
5
C
4
s
4
a
4
t
4
i
4
r
4
Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
New Topic  
Wellz999 Wellz999
wrote...
Go to Answer
Posts: 104
Rep: 0 0
2 years ago
Many mutations in the bithorax gene are known, such as postbithorax, contrabithorax and bithoriaxoid.  Each mutation has a different effect on development of the reduced wing-like T3 appendage, the haltere.  None of these mutations occurs in the coding sequence of bithorax, instead, where are these mutations and how do they effect development?

▸ These mutations alter the slice sites for bithorax and affect the splicing of the bithorax mRNA.  Their different effects on development are cause by affects on alternative splicing.

▸ Each mutant alters a different codon within the bitorax gene, which affects the DNA-binding behavior of the bithorax protein.

▸ These mutations each effect silent sites and effect the stability of the bithorax mRNA.

▸ Bithorax is inhibited by zygotic genes from the mother and these mutations affect maternal genes.

▸ These mutations each effect a different enhancer(s) near the bithorax gene and the resulting misexpression of bithorax in each mutant causes patterning defects in the haltere.
Textbook 
Genetic Analysis: An Integrated Approach

Genetic Analysis: An Integrated Approach


Edition: 3rd
Authors:
Read 39 times
1 Reply
Replies
Answer verified by a subject expert
Hammadsyed14Hammadsyed14
wrote...
#1
Posts: 82
Rep: 0 0
2 years ago
Sign in or Sign up in seconds to unlock everything for free
More solutions for this book are available here
1

Related Topics

Wellz999 Author
wrote...

2 years ago
Thank you, thank you, thank you!
smdavis
wrote...

Yesterday
Thanks
choih94
wrote...

2 hours ago
This helped my grade so much Perfect
New Topic      
Quick Reply
Explore
Post your homework questions and get free online help from our incredible volunteers
  1299 People Browsing
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Live Chat
Related Images
  
 75
  
 16
  
 5