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A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluor

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A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluor

A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluoroquinolone for treatment of this infection. What step of the bacterial DNA replication process is most likely being affected by the use of this medication?
1. It inhibits the enzyme DNA polymerase necessary for DNA replication.
2. It binds to the enzyme topoisomerase IV, preventing the new DNA strands from migrating to opposite sides of the cell, thus preventing bacterial cell replication.
3. It inhibits the relaxation of the supercoil prior to the unwinding process, which terminates replication.
4. It inhibits the unwinding of the two strands of the supercoil, thus terminating replication.

Textbook

Pharmacology: Connections to Nursing Practice

Edition: 3^rd

Authors: Adams, Urban

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First-year pharmacology student, representing MIT!

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ngin

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BreakFree Author

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9 years ago

Sounds and feels right, thank you for the rationale.

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First-year pharmacology student, representing MIT!

ngin

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9 years ago

I've studied this stuff recently, so I knew what the answer was. Good luck with the rest.

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