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prakash prakash
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9 years ago
You are seeing a new patient: A 42 year old male with no major health issues to date has seen a 17 pound gain in weight over the last month. He has been eating from a “fast-food” restaurant regularly and is feeling lethargic. Physical examination indicates muscle weakness. Laboratory results indicate an enlarged liver with excessive glycogen granules and high levels of fat (abnormal fat metabolism), negative for hepatitis and low testosterone levels. He also has abnormal calcium balance in his cells.
What specific organelle is malfunctioning for this patient? Discuss your rationale for your answer (this should be precise and ordered logically). Also discuss what you would advise this patient to do. Although the fast food is an obvious reason for gaining weight, there is an organelle that should still help in metabolizing any food.
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wrote...
9 years ago
The lysosome is generally affected in diseases related to glycogen storage. Since this patient is consuming excessive amounts of fat-rich food items, these molecules are being stored in this particular organelle.
wrote...
9 years ago
Junk foods build up with processed fats inside arteries and in the blood, leading to clogged arteries. The metabolism slows down by intake of junk foods and leads to high blood pressure, high cholesterol, and heart disease. A larger amount of insulin is secreted during the intake of junk foods, which eventually leads to diabetes. Fried foods and fast foods can cause weight gain, muscle pain, and joint pain.

The organelle that is malfunctioning is the smooth endoplasmic reticulum (ER). The smooth ER synthesizes lipids, steroids, and phospholipids. It also involves in the process of detoxification and calcium storage.

Enlarged liver and excessive glycogen granule in the liver causes glycogenosis, which degrades glucose and glycogen synthesis.
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