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dixiechick dixiechick
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11 years ago
What is the significance of cross-linking of among receptors of both naïve B lymphocytes and naive T lymphocytes?
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Staff Member
11 years ago
Hope this is what you're looking for!

Because some large antigens have repeating antigenic determinants that can be processed by B cells without the help of T cells, they are called T-independent antigens. The repeating subunits of T-independent antigens allow extensive cross-linking between numerous BCRs on a B cell, stimulating the B cell to proliferate. T-independent humoral immunity is relatively weak, disappears quickly, and induces little immunological memory.
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