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barry barry
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13 years ago
DNA strands can be pulled apart by adding heat and "melting" the double-stranded DNA. The temperature required to melt a region of DNA changes based on the base-pair composition. Based on the structure of the A-T and C-G bonds in Figure 1.11, which bonds would require more energy (heat) to break them? How might this help you predict which regions of the DNA helix may be the most stable and harder to break apart? (This can be used to predict regions that are not transcribed as often, as you'll see in later chapters.)
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13 years ago
C-G bonds contain three hydrogen bonds, whereas A-T bonds have only two hydrogen bonds. The more hydrogen bonds in a particular region of DNA, the more energy required to break those bonds apart. Thus, regions of DNA with large numbers of C and G residues will be more heat resistant (and probably transcribed less often) than A-T rich regions.
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