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14 years ago
Explain clonal expansion and the roles and interactions of effector cells, memory cells, naive lymphocytes,and plasma cells.
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14 years ago
Clonal expansion is the increase in population of a lymphocyte of a particular antigen specificity, as a result of exposure to that antigen. Lymphocytes produced during clonal expansion differentiate either into effector cells, which produce the immune response and die within a few days, or memory cells, which persist for years and continue to reproduce. Naive lymphocytes are those present at birth, with antigen specificity already determined, but in small numbers because they have not yet been exposed to the antigen and undergone clonal expansion. Plasma cells are the effector B lymphocytes, which become specialized for producing and secreting large amounts of antibody.
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