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ehd123 ehd123
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Posts: 778
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8 years ago
What are the pharmcologic substances that are produced in hypersensitivity reactions like anaphylaxis and what is their source of origin?

I have so far histamines by mast cells. What else might be produced?
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4 Replies
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

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wrote...
#1
Educator
8 years ago Edited: 8 years ago, duddy
Yes, that's true. Anaphylaxis is caused by the release of histamine and other chemicals (I think like 200 other chemicals) from mast cells.

Look up things such as prostaglandin D2 and leukotriene C4
ehd123 Author
wrote...
#2
Valued Member
8 years ago
Yup and tetrapeptides such as eosinophil chemotactic factor, platelet activating factor, kininogenase and cytokines.. Although I am not sure if cytokines are considered pharmacologic substances =/
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#3
Staff Member
8 years ago
Quote from: ehd123 (8 years ago)
Yup and tetrapeptides such as eosinophil chemotactic factor, platelet activating factor, kininogenase and cytokines.. Although I am not sure if cytokines are considered pharmacologic substances =/

They're proteins right. I'd assume so
- Master of Science in Biology
- Bachelor of Science
ehd123 Author
wrote...
#4
Valued Member
8 years ago
Hi duddy
Yep they are proteins.
Will include them then, thanks Slight Smile
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
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