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In diabetes mellitus type 1, blood vessel damage occurs primarily through what process?

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In diabetes mellitus type 1, blood vessel damage occurs primarily through what process?

In diabetes mellitus type 1, blood vessel damage occurs primarily through what process?
A) increase in oxygen levels in blood
B) increase in carbon dioxide build up in blood
C) increase in nitric oxide release from endothelial cells
D) increase in histamine production
E) shear stress on the blood vessels due to elevated pressure

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