× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
New Topic  
Arlena Arlena
wrote...
Posts: 1
Rep: 0 0
7 years ago
Hello,

Our professor said that there is a mistake in the animation of the "Holliday Model of Homologous Recombination" from McGraw Hill (you can find it on youtube or on their site).

The mistake is supposed to be very small and we need to know this for our final exam, so if anyone can find the mistake, please help. The video is only 2 minutes long so it won`t take you long to watch it.

I will be eternally grateful!

Ps: there`s already a discussion on this topic, but the person who started it didn`t write what the mistake in th video is, so I started a new discussion.
Read 148 times
1 Reply

Related Topics

Replies
wrote...
Educator
7 years ago
Keep in mind the following facts:

The current model of the mechanism of exchange of DNA between two homologous chromosomes explains gene conversion and genetic recombination.

1)   A double-stranded DNA molecule undergoes a single-stranded break.

2)   The single-stranded DNA invades the complementary region of the double-stranded homologue.

3)   DNA repair (DNA synthesis) of the dsDNA using the invading ssDNA as template begins.

4)   Reciprocal invasion results in the formation of the "double crossover" or Holliday Junction.

5) Branch migration (movement of the crossover structure) is the result of DNA unwinding and rewinding.

6) Resolution of the Holliday Junction will result in either a cross over event or gene conversion (without a cross over) event.
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  1262 People Browsing
Related Images
  
 78
  
 238
  
 136
Your Opinion
Which is the best fuel for late night cramming?
Votes: 145