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smnam smnam
wrote...
Posts: 128
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11 years ago
1. Action potential propagated across the sarcolemma.
2. Calcium binding to troponin.
3. Exocytosis of acetylcholine.
4. Tropomyosin moved revealing myosin binding sites on actin.
5. Intracellular calcium levels increase in muscle cell.
6. Voltage gated sodium channels opening on the motor neuron.
7. Acetycholine binding to receptors on the sacrolemma.
8. Force generation.
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wrote...
11 years ago
3,7,6,1,5,2,4,8 or 3,7,1,6,5,2,4,8 depending on what your professor has taught you. Technically binding of acetylcholine to receptors on the sarcolemma (7) activates "ligand" gated sodium channels which starts an action potential (1) and this action potential activates "voltage" gated sodium channels so the order is 3,7,1,6. If you professor did not go into so much detail to differentiate between ligand and voltage gated sodium channels, he/she may just want you to understand that acetylcholine activates sodium channels(7 and 6) and causes an action potential across the sarcolemma (1) so the order would be 3,7,6,1. The most technically correct order is 3,7,1,6,5,2,4,8 assuming also that by 1 you mean that action potential on the sarcolemma (muscle cell membrane) (which is what you said) and not the action potential on the motor neuron which causes the exocytosis of acetylcholine. If that last sentence confuses you, don't worry about it, it obviously isn't an issue.
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