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juliabreslin juliabreslin
wrote...
Posts: 96
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11 years ago
 3-cyclopentyl-1-phenylhexane-3-ol

And how is it made of, ie: what Grignard reagent and carbonyl compound are combined to make this molecule? Thanks y'all
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wrote...
11 years ago
Hello,

The structure is

Phenyl CH2CH2C(Cyclopentyl)OHCH2CH2CH3

I would make it with a multi-step reaction.

I would start with butyraldehyde and 2Phenylethylmagnesium bromide

Then with the Grignard reaction,  I would get 1phenylhexane-3-oxomagnesium bromide.

Upon acidification and workup,  I would get 1-phenylhexane-3-ol

This would be oxidized to the ketone,  perhaps by Oppenaur oxidation or some other oxidation to a ketone.

Then,  I would treat that ketone with cyclopentylmagnesium bromide and upon acidification and workup I would get the product desired.

There are other routes one might use but this would, I believe,  use the most easily available starting materials
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