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bogdan bogdan
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6 years ago
Which of the following pathways correctly shows how glycogen synthase is activated in response to the activation of IRS-1 by insulin binding?

A)   IRS-1 causes activation of protein kinase B which phosphorylates glycogen synthase kinase thus preventing phosphorylation of glycogen synthase
B)   IRS-1 activates a cascade that ultimately phosphorylates ERK which then binds to glycogen synthase
C)   IRS-1 activates phosphoinositide 3-kinase and the resulting PIP3 is an allosteric activator of glycogen synthase
D)   IRS-1 activates guanylate cyclase and the resulting cGMP binds to glycogen synthase kinase thus preventing phosphorylation of glycogen synthase
E)   none of the above
Textbook 
Biochemistry

Biochemistry


Edition: 4th
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Captain_MorrigCaptain_Morrig
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6 years ago
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bogdan Author
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6 years ago
Thank you, thank you, thank you!
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Correct Slight Smile TY
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2 hours ago
Thanks for your help!!
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