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Home Q & A Board Biology-Related Homework Help Biochemistry
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wang wang
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Posts: 140
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6 years ago
Some patients with sickle cell disease have relatively mild symptoms because they also have
A:Bone marrow depression
B:elevated beta chain synthesis
C:reduced alfa chain synthesis
D:reduced gamma chain synthesis
E:iron overload
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bio_manbio_man
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#1
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6 years ago
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This verified answer contains over 240 words and 1 attached file(s).
Source  http://sickle.bwh.harvard.edu/scd_background.html
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wang Author
wrote...
#2
6 years ago
I'm not understand why bone marrow depression could let patients with sickle cell disease have mild symptoms.
Why not option B?
wrote...
#3
Educator
6 years ago Edited: 6 years ago, bio_man
I didn't choose b because I found a source that said it's underproduced due to the mutation. If you can find a source that counters that, than b is correct (see the attachment I uploaded above). I figured that since sickle red blood cells are over produced due to their short life span, bone marrow - the location where blood is made - would be affected.
wang Author
wrote...
#4
6 years ago Edited: 6 years ago, wang
well..
Post Merge: 6 years ago

I think bone marrow depression may cause deterioration of sickel cell disease
wrote...
#5
Educator
6 years ago
Also, I just read how bone marrow transplant can cure SCD.

I'm not entirely sure A is correct but it makes the most sense. E and D are impossible.
wang Author
wrote...
#6
6 years ago
Ok :)thank you
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