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Loss-of-function mutations in tumour suppressor genes

kiki-star

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10 years ago

Loss-of-function mutations in tumour suppressor genes

Loss-of-function mutations in tumour suppressor genes (choose any answers that apply):

    a.   are called oncogenes

    b.   are called proto-oncogenes

    c.   are recessive

    d.   are dominant

    e.   do not permit determination of the dominance relationship

    f.   prevent cells from progressing to the next stage of the cell cycle

    g.   prevent cell division

    h.   promote progression to the next stage of the cell cycle

    i.   promote cell division

    j.   are heritable

    k.   are not heritable

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padre

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10 years ago

HI what did you end up putting for this? I'm shooting blanks reading through it.

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Mastering in Nutritional Biology
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kiki-star Author

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10 years ago

I have the basic idea that in normal circumstances tumour suppressor genes stop cell division when something is awry. So when there is a loss of function mutation, it will allow cell division to progress no matter what. As for heritability and dominance still not sure...

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padre

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10 years ago

Quote from: kiki-star (10 years ago)

As for heritability and dominance still not sure...

I suppose it wouldn't be unless it affected the reproductive cells.

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