Section 15 - Home Toxicology

Click to edit Master title style Click to edit Master text styles Second level Third level Fourth level Fifth level Click to edit Master title style Click to edit Master text styles Second level Third level Fourth level Fifth level Click to edit Master text styles Second level Third level Fourth level Fifth level Principles of Pharmacology and Toxicology (BIOL3020) Section 15 Toxicology of Home Products Toxicants in the Home Household products Mold mildew Radon (radiation from ground) Indoor air Second hand smoke Lead Paint solvents Household Hazardous Waste How many household hazardous wastes are in your home (i.e. paints, varnishes, motor oil, pesticides, antifreeze, fluorescent lights) Flammability Reactivity Corrosive (strong acid or base) Toxicity human Toxicity environmental Ingestion Direct ingestion of product Hand to mouth contact Inhalation Acute inhalation of product during use Chronic inhalation of indoor air Skin/eye contact Splashing/spilling during use Violent chemical reactions Contact with treated surfaces More Poisoning Facts Even More Poisoning Facts Common Toxicity Measures LD50 acute ingestion (mg/kg) LC50 acute inhalation (ppm) Draize score skin irritation TLV Threshold Limit Value- chronic inhalation (ppm) Reference dose chronic exposure (mg/kg/day) Oral Toxicity of Common Substances Practically non-toxic ( 15,000 mg/kg) Probable oral lethal dose for 150 lb adult 1 liter modeling clay paraffin wax baby lotion blemish cover (e.g. Clearasil) bone meal cat litter Slightly toxic (5,000 to 15,000 mg/kg) Probable oral lethal dose for 150 lb adult between 500 ml and 1 liter hand dishwashing liquid window cleaner latex house paint soap deodorant (roll-on) white glue (e.g. Elmers) Moderately toxic E F Very toxic Extremely toxic Extremely toxic (5 to 50 mg/kg) Probable oral lethal dose for 150 lb adult 0.1 to 5 ml opium codeine oil of sassafras Super toxic TLVs of Common Ingredients Z Z Carcinogens _ _ Deducing Toxicity Label Information Stick with federally regulated information Signal words only semi-consistent Ignore marketing information Be alert for inconsistencies Signal Words CPSC Consumer Product Safety Commission Health Canada Shortcomings of Label Information Interesting Labels Less-Toxic Alternatives Water-based products Mechanical devices Enzymes instead of solvents Biological pesticides Less-Toxic Alternatives Additional Information B