#1. Use the following information to answer the next two questions.
Refsum Disease
Refsum disease is a genetic disorder that is inherited in an autosomal recessive pattern. Individuals with adult Refsum disease do not have the enzyme to breakdown phytanic acid. As a result, phytanic acid accumulates in the brain, blood, and body tissues. As the disease progresses, individuals with Refsum disease experience loss of vision, hearing, and sense of smell, as well as balance and coordination problems.
In a population, the frequency of the recessive allele for Refsum disease is 0.35. What is the expected frequency of the carriers in this population?
Show all your work. Record your answer as a value between 0 and 1 rounded to two decimal places. (2 marks)
#2. What is the expected frequency of the homozygous dominant genotype for Refsum disease in this population?
Show all your work. Record your answer as a value between 0 and 1 rounded to two decimal places. (2 marks)