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Reverse Genetics Approaches in Model Genetic Organisms

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Table 14.2 Reverse Genetics Approaches in Model Genetic Organisms Species Reverse Genetics Tools Escherichia coli Knockouts by homologous recombination Saccharomyces cerevisiae Knockouts by homologous recombination Arabidopsis thaliana CRISPR; random T-DNA and transposon insertions; TILLING; RNAi Drosophila melanogaster CRISPR; random P element insertion lines; RNAi Caenorhabditis elegans CRISPR; RNAi Ioss-of—function alleles Mus musculus CRISPR; knockouts by homologous recombination; RNAi
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