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Methionine adenosyltransferase

Description
AdoMet is formed from methionine and ATP in an unusual reaction catalyzed by methionine adenosyltransferase, in which ATP is cleaved to yield inorganic triphosphate (PPPi) plus an adenosyl moiety linked directly via the ribose C5 to the methionine sulfur.

The triphosphate is hydrolyzed by the enzyme to pyrophosphate(PPi) and orthophosphate (Pi), drawing the reaction to completion.
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