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SlideshowReport

Structures of human DNA polymerase g (left) and T7 phage DNA polymerase (right) holoenzymes

Description
Both enzymes are shown complexed with DNA.

The pol g structure shows two unique domains (IP and AID, shown in gold), which are involved in DNA binding.

Note the similarity in location of the polymerase and 3’ exonuclease catalytic domains.
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