Simultaneous coinfection of a host cell by two noncomplementing rIIA mutants

No complementation (left) is the common and expected outcome. Rarely, however, intragenic recombination (right) produces wild-type and double-mutant progeny phagesNo complementation (left) is the common and expected outcome. Rarely, however, intragenic recombination (right) produces wild-type and double-mutant progeny phages

Gene A Gene A I I rll mutation V r/l mutation Common, Coinfection no complementation Rare, intragenic crossover A Gene A I :_A: i i z A A A l i GeneA GeneA rll mutant rll mutant I I progeny progeny Double mutant Wild type phage phage l l rll mutant rll wild-type progeny progeny phage phage