Original antigenic sin is best described as a phenomenon in which _____.

Original antigenic sin is best described as a phenomenon in which _____.
 
  a. a highly mutable virus gradually escapes from immunological memory and interferes with compensatory immune responses.
  b. latent viruses periodically activate effector T cells specific for the original antigen recognized in the primary immune response.
  c. the persistence of antigen is necessary to sustain maintenance of immunological memory.
  d. memory T cells no longer express the same profile of adhesion molecules and cytokine receptors compared with the original profile of the naive precursor T cell.