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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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bla32104 bla32104
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6 years ago
Describe the general relationship that may exist between mutations and cancer.
 
  What will be an ideal response?
Textbook 
Essentials of Genetics

Essentials of Genetics


Edition: 9th
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6 years ago
Control of the cell cycle is dependent on a variety of gene-produced proteins such as kinases and cyclins and related factors. Mutations in genes that encode these proteins may disrupt normal cell-cycle control. The G1 checkpoint is altered in some forms of cancer, and mutant cyclins have been shown to be related to a gene product that is overexpressed in some forms of leukemia. Nonmutant genes often suppress the formation of cancer by exerting control over the cell cycle. When mutant, such control may be lost.
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