Selection against self-reactive clones results in the development of tolerance. (True or false?)

Selection against self-reactive clones results in the development of tolerance.
 
  Indicate whether the statement is true or false.

---

In somatic hypermutation, the mutation of immunoglobulin genes occurs at much higher rates than the mutation rates observed in other genes.
 
  Indicate whether the statement is true or false.

---

Affinity maturation is one of the factors responsible for a stronger secondary immune response.
 
  Indicate whether the statement is true or false.

---

In antigen binding, MHC protein binds to the T cell epitope, whereas the TCR binds the MHC motif.
 
  Indicate whether the statement is true or false.

---

Class I MHC proteins have grooves with open ends.
 
  Indicate whether the statement is true or false.