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asaf asaf
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Posts: 32
Rep: 2 0
13 years ago
Hello ! Pleas help me Neutral Face ! the questions:
1. For example, if I know that the duration generation of primate is longer than the duration generation of cow and pig, how can I fix, and calculate again the duration between primate & cow and a pig ?
2.coalescent tree : if we talking about Penny et al tree of proteins we see that all trees are alike , i mean from different louses & in the coalescent tree from different louses we see different trees ,
If there's a contradiction between the argument? Explain?
3. In General what you can say about the frequency of neutral mutation in the population to her (mutation) age?
4. Attached a web site with coalescent tree - http://picasaweb.google.com/asaf2608/Desktop02?authkey=Gv1sRgCLenmqar0rec-AE#5540882004428231810
, in the coalescent tree we have a sampling of 26 Gametes , to be identified 3 allele in specific locus: A allele is common to 2 individuals , B allele is common to 8 individuals, & C allele to the rest of the population , mark on the tree where is it possible that the mutations that speared between alleles may appear ? If there's a most likely place for mutation in allele A?

 8)
Tanks!!!!!
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13 years ago Edited: 13 years ago, sarah
Hey Asaf,

I don't understand your question Undecided. Can you post exactly what is stated by your teacher?

Basically, the probability that two lineages coalesce in the immediately preceding generation is the probability that they share a parent. In a diploid population of constant size with 2N copies of each locus, there are 2N "potential parents" in the previous generation, so the probability that two alleles share a parent is 1/(2N) and correspondingly, the probability that they do not coalesce is 1 - 1/(2N).

I uploaded a calculation that may help you, but I'm not too sure if it will be of any use for you. Also, look at this document: http://www.bieler-beerli.com/downloads/talks/coalescence-I.pdf. It will help you with your understanding; it goes through an example.

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