Wild type, or wt, refers to the genotype that is the typical genotype found in nature. Now read that again. Once more. Now answer.
Answer
- True
False
I PCR out a mutated gene in a patient with nana chorea (the inability to dance in a coordinated fashion) and I compare it to another patient with that same disease phenotype. One subject had a mutation on chromosome 4, and the other subject couldn't rock it because of a mutation on chromosome 5. This is an exampe of
- · pleitropy
· locus heterogeneity
· allelic heterogeneity
· dominant negative mutation
· penetrance
In his experiments, Mendel noted that when two traits are involved in a genetic cross, they are inherited independently of each other. Though Mendel didn't know about chromosomes, this still holds true (mostly) because
- · genes on the same chromosome are often mixed through meiotic crossover during the formation of gametes.
· variant alleles of the same gene do not interfere with the phenotypic expression of the gentoype in different genetic loci.
· most higher organisms are diploid, making only two alleles available for every genetic locus, and there is a 50/50 chance of geting either allele from a single parent.
· expression of phenotypes can vary from the genotypes because of encironmantal influences.
· chromosomes often recombine
Anticipation is caused by a mutation that increases in expressivity over subsequent generations.
Answer
· - True
· False
I have a genotype that should produce a specific phenotype, but some of the individuals with the genotype do not demonstrate any evidence of the phenotype. I would consider this an example of
· allelic heterogeneity.
· locus heterogeneity.
· penetrance.
· expressitivity.
· sheer luck.Which of the following does not occur during the PCR reactions?
Answer
- · Changes in the reaction temperature by a thermocycler
· Denaturation at high temperatures
·
Synthesis of oligonucleotide primers· Extension of primers by DNA polymerase
Annealing of oligonucleotide primers
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